Angiotensin-I Converting Enzyme Inhibitor Activity in Japanese Burdock Roots

  •  Shougo Kawamura    
  •  Takayuki Murakami    
  •  Kohji Ishihara    
  •  Noriyoshi Masuoka    


Japanese burdock roots were extracted with aqueous methanol solution. A compound having the inhibitory activity of angiotensin I-converting enzyme (ACE)[EC] was purified and identified as nicotianamine, (2S, 3’S, 3”S)-N-[N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl]azetidine-2-carboxylic acid. The compound content in burdock roots and related food products were determined. Data revealed that burdock root is a good source of nicotianamine (NA).

This work is licensed under a Creative Commons Attribution 4.0 License.
  • ISSN(Print): 1927-0887
  • ISSN(Online): 1927-0895
  • Started: 2012
  • Frequency: bimonthly

Journal Metrics

Google-based Impact Factor (2019): 0.73

h-index (January 2020): 26

i10-index (January 2020): 128

h5-index (January 2020): 15  

h5-median(January 2020): 19

( The data was calculated based on Google Scholar Citations. Click Here to Learn More. )