Nutritional Value of Raphia hookeri Fruit, Hematological Properties of Its Powder and Aqueous Extract in A Model of Aluminum Chloride Inducing Neurotoxicity by Using Rats
- Hermine Tsafack Doungue
- Anne Pascale Nouemsi Kengne
- Fabrice Tonfack Djikeng
- Gires Boungo Teboukeu
- Hilaire Marcaire Womeni
AbstractThis study was aimed at evaluating the nutritional value of the mesocarp of Raphia hookeri (Rh) fruit and the effect of powder and aqueous extract of the fruit on hematological parameters in rats which have undergone neurotoxicity by aluminum chloride. The nutritional content was evaluated with the standard method. Seven groups of six Wistar rats were used, neurotoxicity was induced by 4.2 mg/kg of body weight of aluminum chloride 3 times a week intraperitonealy with treatment. Rat treatment was as follow: aqueous extract at 200 and 400 mg/kg body weight, 5 and 10% of formulation, negative, positive and normal groups. The experiment lasted 28 days. The data obtained from the nutritive value showed that Rh mesocarp is a good source of lipids (48.97%), fibers (25.82%), calcium (3183.3mg/100g of dry matter), potassium (1218.3 mg/100g of DM), zinc (0.88 mg/100g of DM) and selenium (8.6 mg/100g of DM). Nevertheless, it contains a little amount of phytic acid and hydrocyanic acid which is acceptable for human consumption. It can then be used in many formulations as a source of these nutrients. Aluminum administration indicates the reduction in food intake, a low weight gain and Hematological alteration in the Positive control group. However, consumption of Rh mesocarp indicated an increase in food intake, weight gain and a restoration of hematological parameters to the normal level with the best values in groups that were administered Rh powders (Rh5% and Rh10%). Raphia hookeri mesocarp is a rich source of nutrients involved in the prevention of hematological disorder.
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