Chromosomal Q-Heterochromatin and Sex in Human Population

Ibraimov A. I.

Abstract


Individuals in the population differ from each other on the number, size, location and intensity of fluorescence of Q-heterochromatin regions (Q-HRs) of chromosomes. It is known that there is Y chromosome in a karyotype of males, which contains the largest block of Q-heterochromatin in human genome, and for this reason it is taken for granted that in total there is on average twice more Q-HRs in the genome of male than of female. However, the question on the existence of differences between the sexes on the quantitative content of chromosomal Q-HRs in the population still remains open. The fact is that the Y chromosome differs in its broad interindividual and interpopulation variability on the size of Q-heterochromatin material. A comparative analysis of the amount of chromosomal Q-HRs in the genome of male and female of different racial, ethnic and age groups showed that sex differences at the population level is much more complicated than heretofore assumed.


Full Text: PDF DOI: 10.5539/jmbr.v4n1p10

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Journal of Molecular Biology Research   ISSN 1925-430X (Print)   ISSN 1925-4318 (Online)

 

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