Direct Passerini Reaction of Aldehydes, Isocyanides, and Aliphatic Alcohols Catalyzed by Bismuth (III) Triflate
- Xiao-hua CAI
- Hui GUO
- Bing XIE
Bismuth (III) triflate was found to be effective Lewis acid catalyst for direct alkylative Passerini reaction of
aldehydes, isocyanides, and aliphatic alcohols. In the present reaction, α-unsaturated and aromatic aldehydes used as
substrates produced the corresponding α-alkoxy amide products in good yield.
- Albert JohnEditorial Assistant