Reactions of trans-[Pt(15NH3)2(H2O)2]2+ with Glutathione

Sutopo Hadi, Trevor G. Appleton

Abstract


A study of the reaction between trans-[Pt(15NH3)2(H2O)2](NO3)2 and glutathione (GSH) was undertaken to confirm the identity of the products formed. In alkaline solution, the platinum products observed were mononuclear species, while in acidic solution, the oligomeric products were products obtained. The mass spectrometry of the reaction in alkaline solution showed a sulfur-bridged dinuclear platinum(II) species, trans-[{Pt(SG)2(15NH3)2}2(SG)]+ giving m/z 1380 and the lost of two ammines was observed.


Full Text: PDF DOI: 10.5539/mas.v2n6p30

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.

Modern Applied Science   ISSN 1913-1844 (Print)   ISSN 1913-1852 (Online)

Copyright © Canadian Center of Science and Education

To make sure that you can receive messages from us, please add the 'ccsenet.org' domain to your e-mail 'safe list'. If you do not receive e-mail in your 'inbox', check your 'bulk mail' or 'junk mail' folders.