Abstract

Amaranthus rectroflexus (AmE) and Gnetum africanum (GnA) is the most popular green leafy vegetable in Gabon and is gaining equal popularity as a delicious food leaf in other African countries such as Cameroon, Nigeria, Congo and Angola. The purpose of this study was to assess the impact of these plants in modulating urea, creatinine and plasma electrolytes. 50 mg/kg of aqueous extract were given to rats in the experimental groups for two week, while rats in the control group received an appropriate volume of water. Urea creatinine, and Plasma electrolytes were measured by spectrophotometric method. Chronic oral administration for two week of 50 mg/kg of AmE and GnA aqueous extracts significantly decreased plasma sodium concentration benefit to potassium (P < 0.05). No significant harmful changes (P > 0.05) in weight, blood glucose, creatinine and urea plasma concentration.

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