Angiotensin-I Converting Enzyme Inhibitor Activity in Japanese Burdock Roots


  •  Shougo Kawamura    
  •  Takayuki Murakami    
  •  Kohji Ishihara    
  •  Noriyoshi Masuoka    

Abstract

Japanese burdock roots were extracted with aqueous methanol solution. A compound having the inhibitory activity of angiotensin I-converting enzyme (ACE)[EC 3.4.15.1] was purified and identified as nicotianamine, (2S, 3’S, 3”S)-N-[N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl]azetidine-2-carboxylic acid. The compound content in burdock roots and related food products were determined. Data revealed that burdock root is a good source of nicotianamine (NA).



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  • Issn(Print): 1927-0887
  • Issn(Onlne): 1927-0895
  • Started: 2012
  • Frequency: bimonthly

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