A Case Report of Carbohydrate Antigen 19-9 Producing Advanced Gastric Cancer


  •  Konomi Mizuguchi    
  •  Koichi Sato    
  •  Hiroshi Maekawa    
  •  Mutsumi Sakurada    
  •  Hajime Orita    
  •  Tomoyuki Kushida    
  •  Kouji Senuma    
  •  Tomoaki Ito    
  •  Hirokazu Matsuzawa    
  •  Syunsuke Watanabe    
  •  Satoshi Tokuda    
  •  Syuhei Ueda    
  •  Ryo Wada    

Abstract

The gastric cancer producing carbohydrate antigen 19-9 (CA 19-9) is a rare and unknown that characterize informations.

74-year-old woman who was admitted with complaints of epigastric discomfort. An advanced cancer was found in her lower gastric region; biopsy of the tumor revealed poorly-differentiated adenocarcinoma. Her serum CA 19-9 was extremely elevated at 2322 U/ml and computed tomography demonstrated enlargement of the para-aortic lymph node; thus the tumor was considered unresectable. The patient received 8 cycles of chemotherapy with S-1/cisplatin, which shrank the para-aortic lymph node dramatically, hence she underwent D2 gastrectomy. Immunohistochemical staining of the resected cancer revealed that a third of the cancer cells were positive for CA 19-9. In addition, her serum CA 19-9 decreased rapidly after surgery and she remains alive without recurrence three years after surgery.

We report one high level of CA 19-9 gastric cancer case with dramatically chemosensitive.



This work is licensed under a Creative Commons Attribution 4.0 License.
  • ISSN(Print): 1927-4858
  • ISSN(Online): 1927-4866
  • Started: 2012
  • Frequency: semiannual

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